System shock 2 wiki osa9/21/2023 The role of IOP in the pathogenesis of NTG is an area of controversy prompting research into a variety of IOP independent factors such as vascular dysregulation, hypotension, and lamina cribrosa abnormalities that may have some role to play in the development of this disease. Careful and complete review of history, physical exam findings, and diagnostic testing are key to distinguishing NTG from other common forms of glaucomatous and non-glaucomatous optic neuropathy. ![]() Like POAG, NTG is a chronic, progressive optic neuropathy that results in a characteristic optic nerve head cupping, retinal nerve fiber layer thinning and functional visual field loss. ![]() The clinical characteristics of NTG have many similarities to those in POAG, with a few notable distinctions. Normal tension glaucoma (NTG) is a common form of primary open angle glaucoma (POAG) in which there is no measured elevation of the intraocular pressure (IOP). 3.7.2 Compressive, metabolic, toxic, inflammatory or infectious optic neuropathy.2.3.1 Optic nerve and anatomical features.2.1 Intraocular Pressure in the Population.
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